H-Lee Lab

Publications

Publications

Research Articles

  1. Establishment of the endocrine variant extractor and its clinical application in identifying a novel GATA3 mutation in HDR syndrome

    Y Han, ..., M Noh, H Lee, S Lee

    Frontiers in Endocrinology, 17:1840651, 2026

  2. Oxygen-Dependent Phase Separation of PHD3 Links the Hypoxic Microenvironment to Mitochondrial Metabolic Reprogramming in ccRCC

    J Sim, S Lim, C Lee, HJ Kim, ... TS Choi, H Lee, H Yoon

    Experimental & Molecular Medicine, 2026

  3. Parallel Genome-Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

    S Yun, SY Kim, SG Kim, M Noh, DK Kim, EJ Lee, H Lee

    Advanced Science, e15042, 2025

  4. Dimeric R25CPTH(1–34) activates the parathyroid hormone-1 receptor in vitro and stimulates bone formation in osteoporotic female mice

    M Noh, X Che, X Jin, DK Lee, ... H Lee, TJ Gardella, S Lee

    eLife 13:RP97579, 2025

Reviews

  1. Fungal extracellular vesicles as biomarkers in candidiasis: biogenesis, virulence, and CNS diagnostic applications

    J Choi, ..., H Lee, J Kim

    Frontiers in Cell and Developmental Biology, 14:1854037, 2026

  2. Unlocking biological mechanisms with integrative functional genomics approaches

    S Yun, M Noh, J Yu, HJ Kim, CC Hụi, H Lee, JE Son

    Molecules and Cells 47 (8), 2024

  3. Biogenesis and delivery of extracellular vesicles: harnessing the power of EVs for diagnostics and therapeutics

    J Yu, S Saba, JE Kim, S Yun, HJ Kim, K Jo, J Wright, … H Lee, DK Kim

    Frontiers in Molecular Biosciences (10), 2024

Patents

  • Method for amplifying spacer region of sgRNA

    Inventors:

    HJ Kim, J Yu, H Lee

Papers from Hunsang’s previous lives

  1. Pathogenesis and transmission of SARS-CoV-2 D614G, Alpha, Gamma, Delta, and Omicron variants in golden hamsters

    npj Viruses, 2025

  2. Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors

    Heliyon, 2023

  3. An efficient KRAB domain for CRISPRi applications in human cells

    Nature Methods, 2020

  4. A comprehensive, flexible collection of SARS-CoV-2 coding regions

    G3: Genes, Genomes, Genetics, 2020

  5. Recognition of semaphorin proteins by P. sordellii lethal toxin reveals principles of receptor specificity in clostridial toxins

    Cell, 2020

  6. The Mgr2 subunit of the TIM23 complex regulates membrane insertion of marginal stop-transfer signals in the mitochondrial inner membrane

    FEBS letters, 2020

  7. Molecular insights into the m-AAA protease–mediated dislocation of transmembrane helices in the mitochondrial inner membrane

    Journal of Biological Chemistry, 2017

  8. Membrane topology of transmembrane proteins: determinants and experimental tools

    Biochemical and Biophysical Research Communications, 2014

  9. Live-cell topology assessment of URG7, MRP6102 and SP-C using glycosylatable green fluorescent protein in mammalian cells

    Biochemical and Biophysical Research Communications, 2014

  10. Structural and functional profiling of the lateral gate of the Sec61 translocon

    Journal of Biological Chemistry, 2014

  11. Glycosylatable GFP as a compartment-specific membrane topology reporter

    Biochemical and Biophysical Research Communications, 2012