H-Lee Lab

4

Establishment of the endocrine variant extractor and its clinical application in identifying a novel GATA3 mutation in HDR syndrome

Y Han, ..., M Noh, H Lee, S Lee / Frontiers in Endocrinology, 17:1840651, 2026

3

Oxygen-Dependent Phase Separation of PHD3 Links the Hypoxic Microenvironment to Mitochondrial Metabolic Reprogramming in ccRCC

J Sim, S Lim, C Lee, HJ Kim, ... TS Choi, H Lee, H Yoon / Experimental & Molecular Medicine, 2026

2

Parallel Genome-Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

S Yun, SY Kim, SG Kim, M Noh, DK Kim, EJ Lee, H Lee / Advanced Science, e15042, 2025

1

Dimeric R25CPTH(1–34) activates the parathyroid hormone-1 receptor in vitro and stimulates bone formation in osteoporotic female mice

M Noh, X Che, X Jin, DK Lee, ... H Lee, TJ Gardella, S Lee / eLife 13:RP97579, 2025

3

Fungal extracellular vesicles as biomarkers in candidiasis: biogenesis, virulence, and CNS diagnostic applications

J Choi, ..., H Lee, J Kim / Frontiers in Cell and Developmental Biology, 14:1854037, 2026

2

Unlocking biological mechanisms with integrative functional genomics approaches

S Yun, M Noh, J Yu, HJ Kim, CC Hụi, H Lee, JE Son / Molecules and Cells 47 (8), 2024

1

Biogenesis and delivery of extracellular vesicles: harnessing the power of EVs for diagnostics and therapeutics

J Yu, S Saba, JE Kim, S Yun, HJ Kim, K Jo, J Wright, … H Lee, DK Kim / Frontiers in Molecular Biosciences (10), 2024

1

sgRNA의 spacer region을 증폭하는 방법 / Method for amplifying spacer region of sgRNA

HJ Kim, J Yu, H Lee /

11

Pathogenesis and transmission of SARS-CoV-2 D614G, Alpha, Gamma, Delta, and Omicron variants in golden hamsters

A Banete, BD Griffin, JC Corredor, ... H Lee, ... / npj Viruses 3 :15, 2025

10

Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors

K Chan, AG Farias, H Lee, F Guvenc, P Mero, KR Brown, H Ward, ... / Heliyon 9 (1), 2023

9

An efficient KRAB domain for CRISPRi applications in human cells

N Alerasool, D Segal, H Lee, M Taipale / Nature Methods 17 (11), 1093-1096, 2020

8

A comprehensive, flexible collection of SARS-CoV-2 coding regions

DK Kim, JJ Knapp, D Kuang, A Chawla, P Cassonnet, H Lee, ... / G3: Genes, Genomes, Genetics 10 (9), 3399-3402, 2020

7

Recognition of semaphorin proteins by P. sordellii lethal toxin reveals principles of receptor specificity in clostridial toxins

H Lee, GL Beilhartz, I Kucharska, S Raman, H Cui, MHY Lam, H Liang, ... / Cell 182 (2), 345-356. e16, 2020

6

The Mgr2 subunit of the TIM23 complex regulates membrane insertion of marginal stop‐transfer signals in the mitochondrial inner membrane

S Lee, H Lee, S Yoo, R Ieva, M van der Laan, G von Heijne, H Kim / FEBS letters 594 (6), 1081-1087, 2020

5

Molecular insights into the m-AAA protease–mediated dislocation of transmembrane helices in the mitochondrial inner membrane

S Lee, H Lee, S Yoo, H Kim / Journal of Biological Chemistry 292 (49), 20058-20066, 2017

4

Membrane topology of transmembrane proteins: determinants and experimental tools

H Lee, H Kim / Biochemical and biophysical research communications 453 (2), 268-276, 2014

3

Live-cell topology assessment of URG7, MRP6102 and SP-C using glycosylatable green fluorescent protein in mammalian cells

H Lee, P Lara, A Ostuni, J Presto, J Johansson, IM Nilsson, H Kim / Biochemical and Biophysical Research Communications 450 (4), 1587-1592, 2014

2

Structural and functional profiling of the lateral gate of the Sec61 translocon

JH Reithinger, C Yim, S Kim, H Lee, H Kim / Journal of Biological Chemistry 289 (22), 15845-15855, 2014

1

Glycosylatable GFP as a compartment-specific membrane topology reporter

H Lee, J Min, G von Heijne, H Kim / Biochemical and Biophysical Research Communications 427 (4), 780-784, 2012